Guaianolides matricarin and achillin, acetoxyachillin and leucodin (= desacetoxymatricarin), corresponding C-11 stereoisomers(a),(Z)-2-β-d-glucopyranosyloxy-4-methoxycinnamic acid (cis-GMCA), chlorogenic acid, (E)-2-β-d-glucopyranosyloxy-4-methoxycinnamic acid (trans-GMCA), quercetagetin-7-O-β-d-glucopyranoside, luteolin-7-O-β-d-glucoside, apigenin-7-O-β-d-glucoside, chamaemeloside, apigenin 7-O-(6″-O-acetyl-β-d-glucopyranoside), apigenin] and one polyacetylene (tonghaosu)(b).
Basal cell cancer is the most common type of skin cancer as a result of abnormal growth of the cells in the lowest layer of the epidermis. The cancer rarely spread and kill but can cause significant destruction and disfigurement to the affected skin area and accounted for more than 90% of all skin cancer in the U.S.
According to statistic, skin cancers accounted for approximately 40% of all cancers reported in the United States and approximately 9,500 deaths per year. Herbal chamomile showed to inhibited skin cancer cell lines through its antioxidant effects via inhibition of reactive oxygen species (ROS) type free radicals probably via downregulation of H2O2-generated free radicals in human skin fibroblasts (1). Apigenin , a chemical constituent of flavonoid found in chamomile, with 10 mumoles apigenin in 200 microliters DMSO:acetone (1:9) prior to each UVB exposure showed a promised resulted in reduction incancer incidence (52% inhibition), through absorbing ultraviolet light or decreasing DNA damage(2). In support of the above, the National Taiwan University, indicated that a effectiveness of apigenin, in suppression of 12-0-tetradecanoyl-phorbol-13-acetate-(TPA)-mediated tumor promotion of mouseskin, through vary mechanisms(3).
Ovarian Cysts And PCOS Elimination
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